Chaga Mushroom Health Benefits for Cancer, Inflammation and High Blood Pressure

Chaga fungi have been used for centuries popularly as a herbal tea for medicinal purposes in traditional Russian, Chinese, and Korean medicine.

Exploring the Functional Health Benefits of Chaga Fungus (Inonotus obliquus)

In this blog, we’ll explore the top 9 health benefits of Chaga mushrooms backed by scientific research. From boosting immunity to reducing inflammation, Chaga mushrooms have a lot to offer. Keep reading to learn more about the impressive health benefits of this superfood!

Brief History and Origin of Chaga’s Functional Use

Chaga (Inonotus obliquus), is a sterile conk that grows on birch trees. They prefer cold climates in the northern hemisphere, including Siberia, Alaska, and parts of Canada. The first written record of Chaga’s medicinal use dates back to the 16th century in Russia. Back then, it was known as a “Gift from God”^(1).

People are consuming Chaga mushroom tea for its immune-boosting and anti-inflammatory properties. And for its ability to help with various ailments, including cancer, gastrointestinal issues, and tuberculosis⁽²⁾.

Chaga Mushroom’s Popularity as a Health Food

In recent years, Chaga’s potential health benefits have contributed to its growing popularity as a dietary supplement. These potential health benefits have made Chaga a popular ingredient in dietary supplements and health food products⁽³⁾.

However, as with any dietary supplement, it is important to be mindful of the quality and source of Chaga products. Not all products on the market are created equal. And some may contain low levels of active compounds or harmful contaminants. That is why you should purchase Chaga products from reputable sources.

Top 9 Chaga Mushroom Benefits for Health

1. Chaga for Immune System Boost

Chaga mushrooms may have immune-boosting properties due to the presence of beta-glucans, triterpenes, and polyphenols ⁽⁴⁾. These compounds can stimulate white blood cells, and reduce inflammation, which may help support overall immune system function.

One study published in the International Journal of Medicinal Mushrooms investigated the immune-enhancing effects of Chaga extract in human cells. The researchers found that the extract significantly increased the activity of natural killer cells ⁽⁵⁾. This plays an important role in the immune defense against infections and cancer.

Another study published in the Journal of Medicinal Food found that Chaga extract stimulated the production of cytokines. These are signaling molecules that regulate the immune response. The researchers concluded that Chaga fungi have the potential as an immune-enhancing dietary supplement⁽⁶⁾.

2. The Anti-Inflammatory Properties of Chaga

Chaga mushrooms are also known for their potential anti-inflammatory properties. Inflammation is a natural response to injury or infection. But chronic inflammation can contribute to a range of health issues, including heart disease, cancer, and autoimmune disorders.

Research suggests that the triterpenes and polysaccharides found in Chaga fungi may help reduce inflammation. This happens by inhibiting the production of inflammatory molecules such as cytokines and prostaglandins⁽⁷⁾.

One study published in the International Journal of Biological Macromolecules investigated the anti-inflammatory effects of Chaga fungi extract in a mouse model of acute lung injury. The researchers found that the extract significantly reduced inflammation and oxidative stress in the lungs. This inhibits the production of inflammatory molecules⁽⁸⁾.

Another study published in the Journal of Ethnopharmacology found that Chaga extracts reduced inflammation in human colon cells. This happends by suppressing the activation of NF-κB, a key regulator of inflammation⁽⁹⁾.

These findings suggest that Chaga may have the potential as a natural anti-inflammatory agent. However, more research is needed to fully understand the mechanism of action and effectiveness of Chaga in reducing inflammation in humans.

3. Antioxidant Effects

Chaga fungi are also known for their antioxidant properties. Antioxidants are compounds that protect cells from damage caused by free radicals. Free radicals are unstable molecules that can contribute to chronic diseases such as cancer, heart disease, and Alzheimer’s.

Research suggests that the high levels of polyphenols and triterpenes in Chaga may help neutralize free radicals and protect cells from oxidative stress⁽¹⁰⁾.

One study published in the Journal of Agricultural and Food Chemistry found that Chaga extract had higher antioxidant activity than several other medicinal mushrooms, including shiitake and maitake mushrooms⁽¹¹⁾.

Another study published in the Journal of Medicinal Food investigated the antioxidant effects of Chaga tea in healthy human volunteers. The researchers found that regular consumption of Chaga tea for 4 weeks significantly increased antioxidant activity in the blood⁽¹²⁾.

These findings suggest that Chaga may help protect against oxidative stress and related diseases. However, more research is needed to fully understand the antioxidant effects of Chagas and their potential health benefits in humans.

4. Benefits of Chaga for Cancer

Chaga mushrooms have been studied for their potential to fight cancer. Some preliminary research suggests that the compounds found in Chaga may have anti-tumor effects. It may even help prevent the development of certain types of cancer.

Chaga mushrooms have been studied for their potential to fight cancer. Some preliminary research suggests that the compounds found in Chaga may have anti-tumor effects, making them an interesting subject for diet & nutrition for mesothelioma or other types of cancers. 

One study published in the Journal of Ethnopharmacology investigated the anti-tumor effects of Chaga extract in a mouse model of lung cancer. The researchers found that the extract significantly reduced tumor growth and improved survival rates in the mice⁽¹³⁾.

Another study published in the Journal of Medicinal Food found that Chaga extract inhibited the growth of human colon cancer cells in vitro by inducing apoptosis, a type of programmed cell death⁽¹⁴⁾.

Moreover, a review published in the International Journal of Medicinal Mushrooms has concluded that Chaga may have the potential as a complementary therapy for cancer. This is due to their immune-boosting and anti-tumor effects ⁽¹⁵⁾.

While we need more research to fully understand the anti-cancer properties of Chaga fungi and their potential use in cancer treatment, these preliminary findings suggest that they may have a role to play in cancer prevention and therapy.

5. Lowering Cholesterol Levels

Chaga contains compounds that may have a hypotensive effect, meaning they can lower blood pressure. One such compound is betulinic acid, which can lower blood pressure in a study on rats published in the journal Phytotherapy Research⁽¹⁶⁾.

A study published in the Journal of Ethnopharmacology found that betulinic acid extracted from Chaga significantly reduced total cholesterol, LDL (“bad”) cholesterol, and triglyceride levels in mice fed a high-fat diet.

Another study published in the International Journal of Medicinal Mushrooms found that Chaga extract decreased total cholesterol levels in rats fed a high-cholesterol diet. This is likely due to its antioxidant and anti-inflammatory properties⁽¹⁷⁾.

These studies suggest that Chaga may have the potential as a natural way to lower cholesterol levels and promote cardiovascular health. However, more research is needed to confirm these effects in humans.

6. Anti-Viral Properties

Chaga mushrooms have anti-viral activity against several viruses, including influenza, herpes simplex, and hepatitis C. The polysaccharides and betulinic acid in Chaga can inhibit the replication of these viruses⁽¹⁸⁾.

A study published in the journal Bioorganic & Medicinal Chemistry Letters found that betulinic acid inhibited the replication of the influenza virus in vitro⁽¹⁹⁾. Another study on mice found that a polysaccharide extract of Chaga inhibited the replication of the hepatitis C virus⁽²⁰⁾.

Though preliminary studies show that Chaga mushrooms may have antiviral properties, more research is needed to confirm their effectiveness and safety as a treatment for viral infections.

7. Managing Anxiety and Depression with Chaga

Chaga mushroom contains compounds that may have anti-anxiety and anti-depressant effects. One such compound is ergothioneine. Which shows to have anxiolytic effects in a study on mice published in the journal Behavioural Brain Research⁽²¹⁾.

A study published in the Biomedical Journal in 2018 investigated the potential effects of Chaga extract on anxiety and depression in mice. The researchers found that Chaga extracts significantly reduced symptoms of anxiety and depression-like behavior in the mice⁽²²⁾.

The study suggests that Chaga extract may have the potential as a natural treatment for anxiety and depression in humans. Though, further research is needed to confirm these findings.

8. Supporting Cardiovascular Health

Chaga mushrooms may support cardiovascular health. The primary compound responsible for this benefit is betulinic acid, which shows to have antihypertensive and cholesterol-lowering effects.

In addition, the high levels of antioxidants found in Chaga mushrooms can help reduce inflammation and oxidative stress. These two are the main factors that contribute to cardiovascular disease.

One study published in the Journal of Medicinal Food found that Chaga mushroom extract reduced blood pressure in rats with hypertension. The study suggested that the antihypertensive effect of Chaga extract may be due to its ability to inhibit an enzyme called ACE. This enzyme plays a role in regulating blood pressure⁽²³⁾.

Another study published in the International Journal of Medicinal Mushrooms investigated the effects of Chaga extract on cholesterol levels in mice. The researchers found that Chaga extract significantly lowered total cholesterol, LDL cholesterol, and triglycerides while increasing HDL cholesterol. The study concluded that Chaga extract has the potential as a natural remedy for hyperlipidemia.⁽²⁴⁾.

Overall, these studies suggest that Chaga may have the potential as a natural way to support cardiovascular health. By reducing blood pressure and cholesterol levels. However, more research is needed to fully understand the mechanisms behind these effects and how they may translate to human health.

Final Thoughts on Chaga Mushrooms Health Benefits

Modern research has begun to confirm Chagas’ potential therapeutic uses. They are rich in antioxidants, polysaccharides, and triterpenes. These compounds may help boost the immune system, reduce inflammation, and even have anti-cancer effects. 

While Chaga mushrooms are generally safe for consumption, it’s important to source them from a reputable supplier. Also, avoid consuming them in large amounts.

As with any dietary supplement, it’s always best to consult with a healthcare professional before adding Chaga mushrooms to your diet. Especially if you have a pre-existing medical condition or are taking medications such as blood thinning medications.

Overall, Chaga is a promising natural health food. It may offer numerous health benefits and are worth considering as part of a healthy diet.